Author's response to reviews Title: The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children Authors:
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The STK33-Linked SNP rs4929949 Is Associated with Obesity and BMI in Two Independent Cohorts of Swedish and Greek Children
Recent genome wide association studies (GWAS) have identified a locus on chromosome 11p15.5, closely associated with serine/threonine kinase 33 (STK33), to be associated with body mass. STK33, a relatively understudied protein, has been linked to KRAS mutation-driven cancers and explored as a potential antineoplastic drug target. The strongest association with body mass observed at this loci in...
متن کاملAuthor's response to reviews Title:Chronic disease burden associated with overweight and obesity in Ireland: the effects of a small BMI reduction at population level Authors:
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CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children
Five novel loci recently found to be associated with body mass in two GWAS of East Asian populations were evaluated in two cohorts of Swedish and Greek children and adolescents. These loci are located within, or in the proximity of: CDKAL1, PCSK1, GP2, PAX6 and KLF9. No association with body mass has previously been reported for these loci in GWAS performed on European populations. The single n...
متن کاملSingle Nucleotide Polymorphism (SNP) in the Adiponectin Gene and Cardiovascular Disease
Dear Editor, The recent article by Mohammadzadeh et al.[1] on the latest issue of this Journal showed that the T allele +276G/T SNP of ADIPOQ gene is more associated with the increasing risk of coronary artery disease (CAD) in subjects with type 2 diabetes. Adipocytes were described in myocardial tissue of CAD patients and their role recently discussed[2,3]. Susceptibility to CAD by polymorp...
متن کاملAuthor's response to reviews Title: Pregabalin versus gabapentin in the management of peripheral neuropathic pain associated with post-herpetic neuralgia and diabetic neuropathy: A cost effectiveness analysis for the Greek healthcare setting Authors:
Title: Pregabalin versus gabapentin in the management of peripheral neuropathic pain associated with post-herpetic neuralgia and diabetic neuropathy: A cost effectiveness analysis for the Greek healthcare setting Authors: Kostas Athanasakis ([email protected]) Ioannis Petrakis ([email protected]) Eleftheria Karampli ([email protected]) Elli Vitsou ([email protected]) Le...
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تاریخ انتشار 2012